T-2 mycotoxins can be delivered via food or water sources, as well as, via droplets, aerosols, or smoke from various dispersal systems and exploding munitions. Other names. To investigate the metabolic fate of HT-2 toxin (HT2) and T-2 toxin (T2) in wheat (Triticum aestivum L.), an untargeted metabolomics study utilizing stable isotopic labeling and liquid chromatography–high resolution mass spectrometry was performed.In total, 11 HT2 and 12 T2 derived in planta biotransformation products were annotated putatively. The LD50 of T-2 toxin is approximately 1mg/kg. T-2 mycotoxin is the only toxin produced by fungi known to be used as a biological weapon. Author information: (1)Department of Electrical and Biological Physics, Plasma Bioscience Research Center, Kwangwoon University, Seoul, Republic of Korea. Adhikari M(1), Negi B(2), Kaushik N(3), Adhikari A(4), Al-Khedhairy AA(5), Kaushik NK(1), Choi EH(1). Dairyland Laboratories Inc. is excited to announce our new collaboration with Northwest Labs, LLC, to provide feed and forage testing services from Northwest Lab’s Jerome, Idaho location. If ingested in sufficient quantity, T-2 toxin can severely damage the entire digestive tract and cause rapid death due to internal hemorrhage. The reported LD 50 of T-2 toxin is approximately 1 mg/kg of body weight. Trichothecene mycotoxin (T-2) is a poison produced naturally by four different molds in the environment. fungus which is toxic to humans and animals. T-2 is believed to be at least 100 times more potent than either mustard gas (p. 295) or lewisite (p. 298). It can be used as a biological weapon when mixed with chemicals, heated, and released into the air as an aerosol. It is a naturally occurring mold byproduct of Fusarium spp. In addition to previously reported mono- … It is a naturally occurring mold byproduct of Fusarium spp. ... Mycotoxins are highly diverse secondary metabolites produced in nature by a wide variety of fungus which causes food contamination, resulting in mycotoxicosis in animals and humans. HT-2 toxin is a fusarium mycotoxin (secondary fungal metabolite toxic to human and animals) which may be used as a reference material in systems that detect mycotoxins. T-2 Toxin is a tricothecene produced by species of Fusarium and is one of the more deadly toxins. T-2 mycotoxin: toxicological effects and decontamination strategies. To investigate the metabolic fate of HT-2 toxin (HT2) and T-2 toxin (T2) in wheat (Triticum aestivum L.), an untargeted metabolomics study utilizing stable isotopic labeling and liquid chromatography–high resolution mass spectrometry was performed.In total, 11 HT2 and 12 T2 derived in planta biotransformation products were annotated putatively. The aim of this work was to determine the effects of T-2 toxin and of several of its metabolites, namely HT-2 toxin, neosolaniol, T-2-triol and T-2 tetraol, on two human cells in primary culture: human renal proximal tubule epithelial cells (RPTEC) and normal human lung fibroblasts (NHLF).